Consider the following reaction scheme and choose the correct option(s) for the major products Q, R and S.
(see reaction scheme)
(see reaction scheme)
- (A)(see structure)
- (B)(see structure)
- (C)(see structure)
- (D)(see structure)
Answer: (B)
Solution
The reaction scheme shows a Friedel-Crafts acylation followed by Clemmensen reduction and subsequent transformations.
Starting from the given substrate, the reaction proceeds through:
Option (B) correctly identifies Q as the acid chloride, R as the carboxylic acid/amide, and S as the appropriate cyclic product.
Answer: (B)
Starting from the given substrate, the reaction proceeds through:
- Formation of acid chloride Q
- Friedel-Crafts acylation to give R (an amide or carboxylic acid derivative)
- Intramolecular cyclization under acidic conditions to give S (a cyclic ketone)
Option (B) correctly identifies Q as the acid chloride, R as the carboxylic acid/amide, and S as the appropriate cyclic product.
Answer: (B)
JEE Advanced · 2023 · 04 Jun 2023 · Paper 1 · One or more correct options