JEE Main · 2023 · 10 Apr 2023 · Shift 1 · Biomolecules

The one that does not stabilize

2^{\circ}

and

3^{\circ}

structures of proteins is

(A)H-bonding
(B)-S-S-linkage
(C)-O-O-linkage✓ Correct
(D)van der Waals forces

Answer: (C)

Solution

The secondary and tertiary folding of a protein is held together by hydrogen bonds between backbone and side-chain groups, by disulfide bridges formed between the sulfur atoms of two cysteine residues, by van der Waals contacts and by electrostatic attractions between oppositely charged side chains. A peroxide, or oxygen-oxygen, linkage is not formed between amino-acid residues and takes no part in holding these structures together. The interaction that does not stabilise the secondary and tertiary structure is the oxygen-oxygen linkage.

JEE Main · 2023 · 10 Apr 2023 · Shift 1 · Single correct option

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