Which one of the following chemicals is responsible for the production of HCl in the stomach leading to irritation and pain?
(A)(see structure)
(B)(see structure)✓ Correct
(C)(see structure)
(D)(see structure)
Answer: (B)
Solution
Secretion of hydrochloric acid by the parietal cells of the stomach is stimulated when histamine binds to their H2 receptors, and the excess acid then causes irritation and pain. Histamine, which has an imidazole ring joined to a −CH2CH2NH2 side chain, is the chemical responsible for this acid production.
JEE Main · 2021 · 27 Aug 2021 · Shift 2 · Single correct option