Reagent(s) which can be used to bring about the following transformation is(are)
(A)LiAlH4 in (C2H5)2O
(B)BH3 in THF
(C)NaBH4 in C2H5OH✓ Correct
(D)Raney Ni/H2 in THF✓ Correct
Answer: (C), (D)
Solution
The transformation requires selective reduction of the ketone without affecting the ester or epoxide groups. NaBH4 and Raney Ni/H2 are mild reducing agents that reduce ketones but do not react with esters or epoxides. LiAlH4 and BH3 are strong reducing agents that would also reduce the ester and open the epoxide.
JEE Advanced · 2016 · 22 May 2016 · Paper 2 · One or more correct options